setTimeout

const http2 = require('node:http2');
const client = http2.connect('http://example.org:8000');
const { NGHTTP2_CANCEL } = http2.constants;
const req = client.request({ ':path': '/' });

// Cancel the stream if there's no activity after 5 seconds
req.setTimeout(5000, () => req.close(NGHTTP2_CANCEL));